Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death

BACKGROUND: Apigenin is a flavonoid widely distributed in plant kingdom that exerts cytotoxic effects against a variety of solid and haematological cancers. In this study, we investigated the effect of apigenin against primary effusion lymphoma (PEL), a KSHV-associated B cell lymphoma characterized...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Granato, Marisa, Gilardini Montani, Maria Saveria, Santarelli, Roberta, D’Orazi, Gabriella, Faggioni, Alberto, Cirone, Mara
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704516/
https://ncbi.nlm.nih.gov/pubmed/29179721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0632-z
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