Quercetin Interrupts the Positive Feedback Loop Between STAT3 and IL-6, Promotes Autophagy, and Reduces ROS, Preventing EBV-Driven B Cell Immortalization

The oncogenic gammaherpesvirus Epstein–Barr virus (EBV) immortalizes in vitro B lymphocytes into lymphoblastoid cell lines (LCLs), a model that gives the opportunity to explore the molecular mechanisms driving viral tumorigenesis. In this study, we addressed the potential of quercetin, a widely dist...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Granato, Marisa, Gilardini Montani, Maria Saveria, Zompetta, Claudia, Santarelli, Roberta, Gonnella, Roberta, Romeo, Maria Anele, D’Orazi, Gabriella, Faggioni, Alberto, Cirone, Mara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769872/
https://ncbi.nlm.nih.gov/pubmed/31547402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9090482
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