MYD88 L265P elicits mutation-specific ubiquitination to drive NF-κB activation and lymphomagenesis

Myeloid differentiation primary response protein 88 (MYD88) is a critical universal adapter that transduces signaling from Toll-like and interleukin receptors to downstream nuclear factor-κB (NF-κB). MYD88(L265P) (leucine changed to proline at position 265) is a gain-of-function mutation that occurs...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Yu, Xinfang, Li, Wei, Deng, Qipan, Liu, Haidan, Wang, Xu, Hu, Hui, Cao, Ya, Xu-Monette, Zijun Y., Li, Ling, Zhang, Mingzhi, Lu, Zhongxin, Young, Ken H., Li, Yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2021
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995293/
https://ncbi.nlm.nih.gov/pubmed/33025009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020004918
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi