Expression of the prosurvival kinase HCK requires PAX5 and mutated MYD88 signaling in MYD88-driven B-cell lymphomas

Hematopoietic cell kinase (HCK) is an SRC family member that is aberrantly upregulated in B-cell neoplasms dependent on MYD88-activating mutations and supports their growth and survival. We showed herein that activation of Toll-like receptor (TLR) signaling in MYD88 wild-type B cells also triggered...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Liu, Xia, Chen, Jiaji G., Munshi, Manit, Hunter, Zachary R., Xu, Lian, Kofides, Amanda, Tsakmaklis, Nickolas, Demos, Maria G., Guerrera, Maria Luisa, Chan, Gloria G., Jimenez, Cristina, Patterson, Christopher J., Meid, Kirsten, Keezer, Andrew, Castillo, Jorge J., Treon, Steven P., Yang, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960458/
https://ncbi.nlm.nih.gov/pubmed/31935288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000947
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados