Expression of the prosurvival kinase HCK requires PAX5 and mutated MYD88 signaling in MYD88-driven B-cell lymphomas

Hematopoietic cell kinase (HCK) is an SRC family member that is aberrantly upregulated in B-cell neoplasms dependent on MYD88-activating mutations and supports their growth and survival. We showed herein that activation of Toll-like receptor (TLR) signaling in MYD88 wild-type B cells also triggered...

全面介紹

Na minha lista:
書目詳細資料
發表在:Blood Adv
Main Authors: Liu, Xia, Chen, Jiaji G., Munshi, Manit, Hunter, Zachary R., Xu, Lian, Kofides, Amanda, Tsakmaklis, Nickolas, Demos, Maria G., Guerrera, Maria Luisa, Chan, Gloria G., Jimenez, Cristina, Patterson, Christopher J., Meid, Kirsten, Keezer, Andrew, Castillo, Jorge J., Treon, Steven P., Yang, Guang
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2020
主題:
Lymphoid Neoplasia
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960458/
https://ncbi.nlm.nih.gov/pubmed/31935288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000947
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍