Expression of the prosurvival kinase HCK requires PAX5 and mutated MYD88 signaling in MYD88-driven B-cell lymphomas

Hematopoietic cell kinase (HCK) is an SRC family member that is aberrantly upregulated in B-cell neoplasms dependent on MYD88-activating mutations and supports their growth and survival. We showed herein that activation of Toll-like receptor (TLR) signaling in MYD88 wild-type B cells also triggered...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Blood Adv
Hauptverfasser: Liu, Xia, Chen, Jiaji G., Munshi, Manit, Hunter, Zachary R., Xu, Lian, Kofides, Amanda, Tsakmaklis, Nickolas, Demos, Maria G., Guerrera, Maria Luisa, Chan, Gloria G., Jimenez, Cristina, Patterson, Christopher J., Meid, Kirsten, Keezer, Andrew, Castillo, Jorge J., Treon, Steven P., Yang, Guang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2020
Schlagworte:
Lymphoid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960458/
https://ncbi.nlm.nih.gov/pubmed/31935288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000947
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge