RIP3 mediates TCN-induced necroptosis through activating mitochondrial metabolism and ROS production in chemotherapy-resistant cancers

Resisting cell death is one of the hallmarks of cancer. Necroptosis is a form of non-caspase dependent necrotic cell death mediated by receptor-interacting protein kinase-1/3 (RIP1/3), which represents another mode of programmed cell death besides apoptosis. RIP3 also acts as an energy metabolism re...

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Publicat a:Am J Cancer Res
Autors principals: Zhao, Xu, Quan, Jing, Tan, Yue, Liu, Ying, Liao, Chaoliang, Li, Zhenzhen, Liao, Weihua, Liu, Jikai, Cao, Ya, Luo, Xiangjian
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2021
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994173/
https://ncbi.nlm.nih.gov/pubmed/33791150
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