Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFα and ROS production

Necroptosis/regulated necrosis is a caspase-independent, but receptor interacting protein kinase (RIPK)-dependent form of cell death. In previous studies, neoalbaconol (NA), a constituent extracted from Albatrellus confluens, was demonstrated to induce necroptosis in some cancer cell lines. The mole...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Yu, Xinfang, Deng, Qipan, Li, Wei, Xiao, Lanbo, Luo, Xiangjian, Liu, Xiaolan, Yang, Lifang, Peng, Songling, Ding, Zhihui, Feng, Tao, Zhou, Jian, Fan, Jia, Bode, Ann M., Dong, Zigang, Liu, Jikai, Cao, Ya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385831/
https://ncbi.nlm.nih.gov/pubmed/25575821
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