Attenuated TGFB signalling in macrophages decreases susceptibility to DMBA-induced mammary cancer in mice

BACKGROUND: Transforming growth factor beta1 (TGFB1) is a multi-functional cytokine that regulates mammary gland development and cancer progression through endocrine, paracrine and autocrine mechanisms. TGFB1 also plays roles in tumour development and progression, and its increased expression is ass...

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Publicado en:Breast Cancer Res
Main Authors: Sun, Xuan, Bernhardt, Sarah M., Glynn, Danielle J., Hodson, Leigh J., Woolford, Lucy, Evdokiou, Andreas, Yan, Cong, Du, Hong, Robertson, Sarah A., Ingman, Wendy V.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992865/
https://ncbi.nlm.nih.gov/pubmed/33761981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-021-01417-8
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