Ovarian cycle stage critically affects 21-gene recurrence scores in Mmtv-Pymt mouse mammary tumours

BACKGROUND: The Oncotype DX 21-gene Recurrence Score is predictive of adjuvant chemotherapy benefit for women with early-stage, estrogen receptor (ER)-positive, HER2-negative breast cancer. In premenopausal women, fluctuations in estrogen and progesterone during the menstrual cycle impact gene expre...

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Vydáno v:BMC Cancer
Hlavní autoři: Bernhardt, Sarah M., Dasari, Pallave, Glynn, Danielle J., Woolford, Lucy, Moldenhauer, Lachlan M., Walsh, David, Townsend, Amanda R., Price, Timothy J., Ingman, Wendy V.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236154/
https://ncbi.nlm.nih.gov/pubmed/34174867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-08496-y
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