CCL2-driven inflammation increases mammary gland stromal density and cancer susceptibility in a transgenic mouse model

BACKGROUND: Macrophages play diverse roles in mammary gland development and breast cancer. CC-chemokine ligand 2 (CCL2) is an inflammatory cytokine that recruits macrophages to sites of injury. Although CCL2 has been detected in human and mouse mammary epithelium, its role in regulating mammary glan...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Sun, Xuan, Glynn, Danielle J., Hodson, Leigh J., Huo, Cecilia, Britt, Kara, Thompson, Erik W., Woolford, Lucy, Evdokiou, Andreas, Pollard, Jeffrey W., Robertson, Sarah A., Ingman, Wendy V.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225654/
https://ncbi.nlm.nih.gov/pubmed/28077158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0796-z
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