Attenuated TGFB signalling in macrophages decreases susceptibility to DMBA-induced mammary cancer in mice

BACKGROUND: Transforming growth factor beta1 (TGFB1) is a multi-functional cytokine that regulates mammary gland development and cancer progression through endocrine, paracrine and autocrine mechanisms. TGFB1 also plays roles in tumour development and progression, and its increased expression is ass...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Sun, Xuan, Bernhardt, Sarah M., Glynn, Danielle J., Hodson, Leigh J., Woolford, Lucy, Evdokiou, Andreas, Yan, Cong, Du, Hong, Robertson, Sarah A., Ingman, Wendy V.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992865/
https://ncbi.nlm.nih.gov/pubmed/33761981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-021-01417-8
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