FSMP-07. CYSTATHIONINE-Γ-LYASE DRIVES ANTIOXIDANT DEFENSE IN CYSTEINE-RESTRICTED IDH1 MUTANT ASTROCYTOMAS

Mutations in isocitrate dehydrogenase 1 or 2 (IDH1/2) define glioma subtypes and are considered primary events in gliomagenesis, impacting tumor epigenetics and metabolism. IDH enzymes are crucial for the generation of reducing potential, yet the impact of the mutation on the cellular antioxidant sy...

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Détails bibliographiques
Publié dans:Neurooncol Adv
Auteurs principaux: Cano-Galiano, Andrés, Oudin, Anais, Fack, Fred, Allega, Maria-Francesca, Sumpton, David, Martinez-Garcia, Elena, Dittmar, Gunnar, Hau, Ann-Christin, Herold-Mende, Christel, Bjerkvig, Rolf, Meiser, Johannes, Tardito, Saverio, Niclou, Simone P
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
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Supplement Abstracts
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992224/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.071
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