Ebola virus glycoprotein interacts with cholesterol to enhance membrane fusion and cell entry

Cholesterol serves critical roles in enveloped virus fusion by modulating membrane properties. The glycoprotein (GP) of Ebola virus (EBOV) promotes fusion in the endosome, a process that requires the endosomal cholesterol transporter NPC1. However, the role of cholesterol in EBOV fusion is unclear....

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Detaylı Bibliyografya
Yayımlandı:Nat Struct Mol Biol
Asıl Yazarlar: Lee, Jinwoo, Kreutzberger, Alex J. B., Odongo, Laura, Nelson, Elizabeth A., Nyenhuis, David A., Kiessling, Volker, Liang, Binyong, Cafiso, David S., White, Judith M., Tamm, Lukas K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992113/
https://ncbi.nlm.nih.gov/pubmed/33462517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-00548-4
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