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Ebola virus glycoprotein interacts with cholesterol to enhance membrane fusion and cell entry
Cholesterol serves critical roles in enveloped virus fusion by modulating membrane properties. The glycoprotein (GP) of Ebola virus (EBOV) promotes fusion in the endosome, a process that requires the endosomal cholesterol transporter NPC1. However, the role of cholesterol in EBOV fusion is unclear....
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| Publicado no: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7992113/ https://ncbi.nlm.nih.gov/pubmed/33462517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-00548-4 |
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