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Conserved arginine residues in synaptotagmin 1 regulate fusion pore expansion through membrane contact
Synaptotagmin 1 is a vesicle-anchored membrane protein that functions as the Ca(2+) sensor for synchronous neurotransmitter release. In this work, an arginine containing region in the second C2 domain of synaptotagmin 1 (C2B) is shown to control the expansion of the fusion pore and thereby the conce...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7859215/ https://ncbi.nlm.nih.gov/pubmed/33536412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21090-x |
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