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A molecular mechanism for calcium/synaptotagmin-triggered exocytosis

The regulated exocytotic release of neurotransmitter and hormones is accomplished by a complex protein machinery consisting in its core of SNARE proteins and the calcium sensor synaptotagmin-1. We propose a mechanism where the lipid membrane is intimately involved in coupling calcium sensing to rele...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Kiessling, Volker, Kreutzberger, Alex J.B., Liang, Binyong, Nyenhuis, Sarah B., Seelheim, Patrick, Castle, J. David, Cafiso, David S., Tamm, Lukas K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176490/
https://ncbi.nlm.nih.gov/pubmed/30291360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0130-9
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