Drugging DNA Damage Repair Pathways for Trinucleotide Repeat Expansion Diseases

DNA damage repair (DDR) mechanisms have been implicated in a number of neurodegenerative diseases (both genetically determined and sporadic). Consistent with this, recent genome-wide association studies in Huntington’s disease (HD) and other trinucleotide repeat expansion diseases have highlighted g...

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Bibliographic Details
Published in:J Huntingtons Dis
Main Authors: Benn, Caroline L., Gibson, Karl R., Reynolds, David S.
Format: Artigo
Language:Inglês
Published: IOS Press 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990437/
https://ncbi.nlm.nih.gov/pubmed/32925081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-200421
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