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DNA Mismatch Repair and its Role in Huntington’s Disease
DNA mismatch repair (MMR) is a highly conserved genome stabilizing pathway that corrects DNA replication errors, limits chromosomal rearrangements, and mediates the cellular response to many types of DNA damage. Counterintuitively, MMR is also involved in the generation of mutations, as evidenced by...
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| Veröffentlicht in: | J Huntingtons Dis |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
IOS Press
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7990411/ https://ncbi.nlm.nih.gov/pubmed/33579865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-200438 |
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