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DNA Mismatch Repair and its Role in Huntington’s Disease

DNA mismatch repair (MMR) is a highly conserved genome stabilizing pathway that corrects DNA replication errors, limits chromosomal rearrangements, and mediates the cellular response to many types of DNA damage. Counterintuitively, MMR is also involved in the generation of mutations, as evidenced by...

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Detalhes bibliográficos
Publicado no:J Huntingtons Dis
Main Authors: Iyer, Ravi R., Pluciennik, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990411/
https://ncbi.nlm.nih.gov/pubmed/33579865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-200438
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