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DNA Triplet Repeat Expansion and Mismatch Repair

DNA mismatch repair is a conserved antimutagenic pathway that maintains genomic stability through rectification of DNA replication errors and attenuation of chromosomal rearrangements. Paradoxically, mutagenic action of mismatch repair has been implicated as a cause of triplet repeat expansions that...

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Detalhes bibliográficos
Publicado no:Annu Rev Biochem
Main Authors: Iyer, Ravi R., Pluciennik, Anna, Napierala, Marek, Wells, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845744/
https://ncbi.nlm.nih.gov/pubmed/25580529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-060614-034010
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