A carregar...
HDAC3 deacetylates the DNA mismatch repair factor MutSβ to stimulate triplet repeat expansions
Trinucleotide repeat (TNR) expansions cause nearly 20 severe human neurological diseases which are currently untreatable. For some of these diseases, ongoing somatic expansions accelerate disease progression and may influence age of onset. This new knowledge emphasizes the importance of understandin...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7519323/ https://ncbi.nlm.nih.gov/pubmed/32900932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013223117 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|