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Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba

Naegleria fowleri is a pathogenic, thermophilic, free-living amoeba which causes primary amebic meningoencephalitis (PAM). Penetrating the olfactory mucosa, the brain-eating amoeba travels along the olfactory nerves, burrowing through the cribriform plate to its destination: the brain’s frontal lobe...

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Publicat a:PLoS One
Autors principals: Tillery, Logan, Barrett, Kayleigh, Goldstein, Jenna, Lassner, Jared W., Osterhout, Bram, Tran, Nathan L., Xu, Lily, Young, Ryan M., Craig, Justin, Chun, Ian, Dranow, David M., Abendroth, Jan, Delker, Silvia L., Davies, Douglas R., Mayclin, Stephen J., Calhoun, Brandy, Bolejack, Madison J., Staker, Bart, Subramanian, Sandhya, Phan, Isabelle, Lorimer, Donald D., Myler, Peter J., Edwards, Thomas E., Kyle, Dennis E., Rice, Christopher A., Morris, James C., Leahy, James W., Manetsch, Roman, Barrett, Lynn K., Smith, Craig L., Van Voorhis, Wesley C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990177/
https://ncbi.nlm.nih.gov/pubmed/33760815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241738
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