Enzymatic and Structural Characterization of the Naegleria fowleri Glucokinase

Infection with the free-living amoeba Naegleria fowleri leads to life-threatening primary amoebic meningoencephalitis. Efficacious treatment options for these infections are limited, and the mortality rate is very high (∼98%). Parasite metabolism may provide suitable targets for therapeutic design....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Milanes, Jillian E., Suryadi, Jimmy, Abendroth, Jan, Van Voorhis, Wesley C., Barrett, Kayleigh F., Dranow, David M., Phan, Isabelle Q., Patrick, Stephen L., Rozema, Soren D., Khalifa, Muhammad M., Golden, Jennifer E., Morris, James C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2019
Gaiak:
Experimental Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496100/
https://ncbi.nlm.nih.gov/pubmed/30783001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02410-18
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