Enzymatic and Structural Characterization of the Naegleria fowleri Glucokinase

Infection with the free-living amoeba Naegleria fowleri leads to life-threatening primary amoebic meningoencephalitis. Efficacious treatment options for these infections are limited, and the mortality rate is very high (∼98%). Parasite metabolism may provide suitable targets for therapeutic design....

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Milanes, Jillian E., Suryadi, Jimmy, Abendroth, Jan, Van Voorhis, Wesley C., Barrett, Kayleigh F., Dranow, David M., Phan, Isabelle Q., Patrick, Stephen L., Rozema, Soren D., Khalifa, Muhammad M., Golden, Jennifer E., Morris, James C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496100/
https://ncbi.nlm.nih.gov/pubmed/30783001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02410-18
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