Enzymatic and Structural Characterization of the Naegleria fowleri Glucokinase

Infection with the free-living amoeba Naegleria fowleri leads to life-threatening primary amoebic meningoencephalitis. Efficacious treatment options for these infections are limited, and the mortality rate is very high (∼98%). Parasite metabolism may provide suitable targets for therapeutic design....

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Milanes, Jillian E., Suryadi, Jimmy, Abendroth, Jan, Van Voorhis, Wesley C., Barrett, Kayleigh F., Dranow, David M., Phan, Isabelle Q., Patrick, Stephen L., Rozema, Soren D., Khalifa, Muhammad M., Golden, Jennifer E., Morris, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496100/
https://ncbi.nlm.nih.gov/pubmed/30783001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02410-18
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