Enzymatic and Structural Characterization of the Naegleria fowleri Glucokinase

Infection with the free-living amoeba Naegleria fowleri leads to life-threatening primary amoebic meningoencephalitis. Efficacious treatment options for these infections are limited, and the mortality rate is very high (∼98%). Parasite metabolism may provide suitable targets for therapeutic design....

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Milanes, Jillian E., Suryadi, Jimmy, Abendroth, Jan, Van Voorhis, Wesley C., Barrett, Kayleigh F., Dranow, David M., Phan, Isabelle Q., Patrick, Stephen L., Rozema, Soren D., Khalifa, Muhammad M., Golden, Jennifer E., Morris, James C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Experimental Therapeutics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496100/
https://ncbi.nlm.nih.gov/pubmed/30783001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02410-18
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