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Knockdown of CLN5 inhibits the tumorigenic properties of glioblastoma cells via the Akt/mTOR signaling pathway

Gliomas are highly malignant tumors with a rapid progression and poor prognosis. The present study investigated the cellular effects of CLN5-knockdown in the glioblastoma (GBM) U251 and U87MG cell lines. The Cell Counting Kit-8 and colony formation assays indicated that CLN5-knockdown inhibited the...

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Bibliografische gegevens
Gepubliceerd in:Oncol Lett
Hoofdauteurs: Xing, Jiexia, Li, Ying, Zhao, Huilan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988714/
https://ncbi.nlm.nih.gov/pubmed/33777210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12648
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