PKD knockdown inhibits pressure overload-induced cardiac hypertrophy by promoting autophagy via AKT/mTOR pathway

Growing evidence shows that protein kinase D (PKD) plays an important role in the development of pressure overload-induced cardiac hypertrophy. However, the mechanisms involved are not clear. This study tested our hypothesis that PKD might mediate cardiac hypertrophy by negatively regulating autopha...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Zhao, Di, Wang, Wei, Wang, Hao, Peng, Honghai, Liu, Xiangjuan, Guo, Weixing, Su, Guohai, Zhao, Zhuo
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370435/
https://ncbi.nlm.nih.gov/pubmed/28367092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.17617
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