The Akt-mTOR axis is a pivotal regulator of eccentric hypertrophy during volume overload

The heart has two major modalities of hypertrophy in response to hemodynamic loads: concentric and eccentric hypertrophy caused by pressure and volume overload (VO), respectively. However, the molecular mechanism of eccentric hypertrophy remains poorly understood. Here we demonstrate that the Akt-ma...

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Publicado no:Sci Rep
Main Authors: Ikeda, Masataka, Ide, Tomomi, Fujino, Takeo, Matsuo, Yuka, Arai, Shinobu, Saku, Keita, Kakino, Takamori, Oga, Yasuhiro, Nishizaki, Akiko, Sunagawa, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626834/
https://ncbi.nlm.nih.gov/pubmed/26515499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15881
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