Synergistic antitumor effect of the anti-ErbB2 antibodies trastuzumab and H2-18 on trastuzumab-resistant gastric cancer cells

Trastuzumab resistance is a severe problem in the treatment of ErbB2-amplified cancer. Although trastuzumab plus pertuzumab is able to partly overcome trastuzumab resistance in ErbB2-overexpressing cancer, its antitumor efficacy remains limited. The present study investigated the antitumor activity...

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Udgivet i:Oncol Lett
Main Authors: Wang, Chao, Wang, Lingfei, Liang, Beibei, Zhou, Bo, Sun, Yu, Meng, Yanchun, Dong, Jian, Chen, Lin, Li, Bohua
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2021
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988693/
https://ncbi.nlm.nih.gov/pubmed/33777223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12661
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