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Combating acquired resistance to trastuzumab by an anti-ErbB2 fully human antibody
Trastuzumab resistance is a common problem that impedes the effectiveness of trastuzumab in ErbB2-amplified cancers. About 70% of ErbB2-amplified breast cancers do not respond to trastuzumab (de novo resistance), and the majority of the trastuzumab-responsive cancers progress within 1 year (acquired...
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| Publicado no: | Oncotarget |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5522102/ https://ncbi.nlm.nih.gov/pubmed/28514745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17451 |
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