Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody

Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection represents a global health crisis. Immune cell activation via pattern recognition receptors has been implicated as a driver of the hyperinflammatory response seen in COVID-19. However, our understanding of the specific immune respons...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Gebremeskel, Simon, Schanin, Julia, Coyle, Krysta M., Butuci, Melina, Luu, Thuy, Brock, Emily C., Xu, Alan, Wong, Alan, Leung, John, Korver, Wouter, Morin, Ryan D., Schleimer, Robert P., Bochner, Bruce S., Youngblood, Bradford A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988091/
https://ncbi.nlm.nih.gov/pubmed/33777047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.650331
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