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Adipocyte PHLPP2 inhibition prevents obesity-induced fatty liver
Increased adiposity confers risk for systemic insulin resistance and type 2 diabetes (T2D), but mechanisms underlying this pathogenic inter-organ crosstalk are incompletely understood. We find PHLPP2 (PH domain and leucine rich repeat protein phosphatase 2), recently identified as the Akt Ser473 pho...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7988046/ https://ncbi.nlm.nih.gov/pubmed/33758172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22106-2 |
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