PNPLA3 I148M Variant Influences Circulating Retinol in Adults with Nonalcoholic Fatty Liver Disease or Obesity(1)(2)

Background: Retinol is a lipid-soluble essential nutrient that is stored as retinyl esters in lipid droplets of hepatic stellate cells. Patatin-like phospholipase domain-containing 3 (PNPLA3), through its retinyl-palmitate lipase activity, releases retinol from lipid droplets in hepatic stellate cel...

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Publicat a:J Nutr
Autors principals: Mondul, Alison, Mancina, Rosellina M, Merlo, Andrea, Dongiovanni, Paola, Rametta, Raffaela, Montalcini, Tiziana, Valenti, Luca, Albanes, Demetrius, Romeo, Stefano
Format: Artigo
Idioma:Inglês
Publicat: American Society for Nutrition 2015
Matèries:
Biochemical, Molecular, and Genetic Mechanisms
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516767/
https://ncbi.nlm.nih.gov/pubmed/26136587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.115.210633
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