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PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons

Recent evidence suggests neurogenesis is on-going throughout life but the relevance of these findings for neurodegenerative disorders such as Parkinson’s disease (PD) is poorly understood. Biallelic PINK1 mutations cause early onset, Mendelian inherited PD. We studied the effect of PINK1 deficiency...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Brown, Sarah J., Boussaad, Ibrahim, Jarazo, Javier, Fitzgerald, Julia C., Antony, Paul, Keatinge, Marcus, Blechman, Janna, Schwamborn, Jens C., Krüger, Rejko, Placzek, Marysia, Bandmann, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988014/
https://ncbi.nlm.nih.gov/pubmed/33758225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84278-7
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