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Quality Control Strategy for CRISPR-Cas9-Based Gene Editing Complicated by a Pseudogene
CRISPR-Cas9 mediated gene editing in induced pluripotent stem cells became an efficient tool to investigate biological mechanisms underlying genetic-driven diseases while accounting for the respective genetic background. This technique relies on the targeting of a specific nucleotide sequence presen...
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| 發表在: | Front Genet |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6961559/ https://ncbi.nlm.nih.gov/pubmed/31998363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01297 |
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