Impaired mitochondrial–endoplasmic reticulum interaction and mitophagy in Miro1-mutant neurons in Parkinson’s disease

Mitochondrial Rho GTPase 1 (Miro1) protein is a well-known adaptor for mitochondrial transport and also regulates mitochondrial quality control and function. Furthermore, Miro1 was associated with mitochondrial-endoplasmic reticulum (ER) contact sites (MERCs), which are key regulators of cellular ca...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Berenguer-Escuder, Clara, Grossmann, Dajana, Antony, Paul, Arena, Giuseppe, Wasner, Kobi, Massart, François, Jarazo, Javier, Walter, Jonas, Schwamborn, Jens C, Grünewald, Anne, Krüger, Rejko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
General Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254851/
https://ncbi.nlm.nih.gov/pubmed/32280985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa066
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