Synthesis and Preliminary Evaluation of (211)At-labeled Inhibitors of Prostate-Specific Membrane Antigen for Targeted Alpha Particle Therapy of Prostate Cancer

INTRODUCTION: The high potency and short tissue range of α-particles are attractive features for targeted radionuclide therapy, particularly for cancers with micro-metastases. In the current study, we describe the synthesis of a series of (211)At-labeled prostate-specific membrane antigen (PSMA) inh...

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Publicat a:Nucl Med Biol
Autors principals: Vaidyanathan, Ganesan, Mease, Ronnie C., Minn, Il, Choi, Jaeyeon, Chen, Ying, Shallal, Hassan, Kang, Choong Mo, McDougald, Darryl, Kumar, Vivek, Pomper, Martin G., Zalutsky, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987787/
https://ncbi.nlm.nih.gov/pubmed/33601187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2021.01.002
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