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Synthesis and Evaluation of 4-[(18)F]Fluoropropoxy-3-iodobenzylguanidine ([(18)F]FPOIBG): A Novel (18)F-labeled Analogue of MIBG

INTRODUCTION: Radioiodinated meta-iodobenzylguanidine (MIBG), a norepinephrine transporter (NET) substrate, has been extensively used as an imaging agent to study the pathophysiology of the heart and for the diagnosis and treatment of neuroendocrine tumors. The goal of this study was to develop an (...

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Détails bibliographiques
Publié dans:Nucl Med Biol
Auteurs principaux: Vaidyanathan, Ganesan, McDougald, Darryl, Koumarianou, Eftychia, Choi, Jaeyeon, Hens, Marc, Zalutsky, Michael R.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481138/
https://ncbi.nlm.nih.gov/pubmed/25956997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2015.04.005
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