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N-Succinimidyl 3-((4-(4-[(18)F]fluorobutyl)-1H-1,2,3-triazol-1-yl)methyl)-5-(guanidinomethyl)benzoate ([(18)F]SFBTMGMB): A Residualizing Label for (18)F-labeling of internalizing biomolecules

Residualizing labeling methods for internalizing peptides and proteins are designed to trap the radionuclide inside the cell after intracellular degradation of the biomolecule. The goal of this work was to develop a residualizing label for the (18)F-labeling of internalizing biomolecules based on a...

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Publicat a:Org Biomol Chem
Autors principals: Vaidyanathan, Ganesan, McDougald, Darryl, Choi, Jaeyeon, Pruszynski, Marek, Koumarianou, Eftychia, Zhou, Zhengyuan, Zalutsky, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720566/
https://ncbi.nlm.nih.gov/pubmed/26645790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob02258d
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