Lymphocyte Activation Gene 3 (Lag3) Contributes to α-Synucleinopathy in α-Synuclein Transgenic Mice

Aggregation of misfolded α-synuclein (α-syn) is the major component of Lewy bodies and neurites in Parkinson’s disease (PD) and related α-synucleinopathies. Some α-syn mutations (e.g., A53T) in familial PD recapitulate the α-syn pathology in transgenic mice, which supports the importance of patholog...

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Dettagli Bibliografici
Pubblicato in:Front Cell Neurosci
Autori principali: Gu, Hao, Yang, Xiuli, Mao, Xiaobo, Xu, Enquan, Qi, Chen, Wang, Haibo, Brahmachari, Saurav, York, Bethany, Sriparna, Manjari, Li, Amanda, Chang, Michael, Patel, Pavan, Dawson, Valina L., Dawson, Ted M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987675/
https://ncbi.nlm.nih.gov/pubmed/33776654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.656426
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