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Genome-Editing Strategies for Treating Human Retinal Degenerations

Inherited retinal degenerations (IRDs) are a leading cause of blindness. Although gene-supplementation therapies have been developed, they are only available for a small proportion of recessive IRD mutations. In contrast, genome editing using clustered-regularly interspaced short palindromic repeats...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Quinn, Joel, Musa, Ayesha, Kantor, Ariel, McClements, Michelle E., Cehajic-Kapetanovic, Jasmina, MacLaren, Robert E., Xue, Kanmin
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987357/
https://ncbi.nlm.nih.gov/pubmed/32993386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2020.231
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