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Engineering synthetic morphogen systems that can program multicellular patterning

In metazoan tissues, cells decide their fates by sensing positional information provided by specialized morphogen proteins. To explore what features are sufficient for positional encoding, we asked whether arbitrary molecules (e.g., green fluorescent protein or mCherry) could be converted into synth...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Science
Päätekijät: Toda, Satoshi, McKeithan, Wesley L., Hakkinen, Teemu J., Lopez, Pilar, Klein, Ophir D., Lim, Wendell A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986291/
https://ncbi.nlm.nih.gov/pubmed/33060357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc0033
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