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Programming self-organizing multicellular structures with synthetic cell-cell signaling

A common theme in the self-organization of multicellular tissues is the use of cell-cell signaling networks to induce morphological changes. We used the modular synNotch juxtacrine signaling platform to engineer artificial genetic programs in which specific cell-cell contacts induced changes in cadh...

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Bibliografische gegevens
Gepubliceerd in:Science
Hoofdauteurs: Toda, Satoshi, Blauch, Lucas R., Tang, Sindy K. Y., Morsut, Leonardo, Lim, Wendell A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492944/
https://ncbi.nlm.nih.gov/pubmed/29853554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat0271
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