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Programming self-organizing multicellular structures with synthetic cell-cell signaling
A common theme in the self-organization of multicellular tissues is the use of cell-cell signaling networks to induce morphological changes. We used the modular synNotch juxtacrine signaling platform to engineer artificial genetic programs in which specific cell-cell contacts induced changes in cadh...
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| Publicado en: | Science |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6492944/ https://ncbi.nlm.nih.gov/pubmed/29853554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat0271 |
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