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Designing Synthetic Regulatory Networks Capable of Self-Organizing Cell Polarization
How cells form global, self-organized structures using genetically encoded molecular rules remains elusive. Here, we take a synthetic biology approach to investigate the design principles governing cell polarization. First, using a coarse-grained computational model, we searched for all possible sim...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3498761/ https://ncbi.nlm.nih.gov/pubmed/23039994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.08.040 |
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