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Engineering synthetic morphogen systems that can program multicellular patterning

In metazoan tissues, cells decide their fates by sensing positional information provided by specialized morphogen proteins. To explore what features are sufficient for positional encoding, we asked whether arbitrary molecules (e.g., green fluorescent protein or mCherry) could be converted into synth...

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Библиографические подробности
Опубликовано в: :Science
Главные авторы: Toda, Satoshi, McKeithan, Wesley L., Hakkinen, Teemu J., Lopez, Pilar, Klein, Ophir D., Lim, Wendell A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986291/
https://ncbi.nlm.nih.gov/pubmed/33060357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc0033
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