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Engineering synthetic morphogen systems that can program multicellular patterning

In metazoan tissues, cells decide their fates by sensing positional information provided by specialized morphogen proteins. To explore what features are sufficient for positional encoding, we asked whether arbitrary molecules (e.g., green fluorescent protein or mCherry) could be converted into synth...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Toda, Satoshi, McKeithan, Wesley L., Hakkinen, Teemu J., Lopez, Pilar, Klein, Ophir D., Lim, Wendell A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986291/
https://ncbi.nlm.nih.gov/pubmed/33060357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc0033
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