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SIRT6-specific inhibitor OSS-128167 exacerbates diabetic cardiomyopathy by aggravating inflammation and oxidative stress

Diabetic cardiomyopathy (DCM) is a serious complication of diabetes, which importantly contributes to the increased mortality of patients with diabetes. The development of DCM is accompanied by numerous pathological mechanisms, including oxidative stress and chronic inflammation. Accordingly, the pr...

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Опубликовано в: :Mol Med Rep
Главные авторы: Huang, Yibo, Zhang, Junkai, Xu, Dongdong, Peng, Yu, Jin, Yuan, Zhang, Lei
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986000/
https://ncbi.nlm.nih.gov/pubmed/33760202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12006
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