SIRT6 Inhibitor, OSS_128167 Restricts Hepatitis B Virus Transcription and Replication Through Targeting Transcription Factor Peroxisome Proliferator-Activated Receptors α

Hepatitis B virus (HBV) is a major public health threat and anti-HBV drugs are limited to nucleos(t)ide analogs (NAs) and pegylated interferon alpha (Peg-IFNα). Toward identifying an effective compound for HBV treatment is important to suppress and eradicate HBV. In this study, we explored the anti-...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Jiang, Hui, Cheng, Sheng-Tao, Ren, Ji-Hua, Ren, Fang, Yu, Hai-Bo, Wang, Qing, Huang, Ai-Long, Chen, Juan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823301/
https://ncbi.nlm.nih.gov/pubmed/31708789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01270
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