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AGK2, A SIRT2 Inhibitor, Inhibits Hepatitis B Virus Replication In Vitro And In Vivo
Sirtuin 2 (SIRT2) is a nicotinamide adenine dinucleotide (NAD( +))-dependent class III histone deacetylase. We have reported that HBx (hepatitis B virus X protein)-elevated SIRT2 promotes HBV replication and hepatocarcinogenesis. However, the potential anti-HBV effect of AGK2, a selective inhibitor...
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| Veröffentlicht in: | Int J Med Sci |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Ivyspring International Publisher
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6158674/ https://ncbi.nlm.nih.gov/pubmed/30275764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.26125 |
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