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FGF21 deletion exacerbates diabetic cardiomyopathy by aggravating cardiac lipid accumulation

Fibroblast growth factor 21 (FGF21) plays an important role in energy homoeostasis. The unaddressed question of FGF21’s effect on the development and progression of diabetic cardiomyopathy (DCM) is investigated here with FGF21 knockout (FGF21KO) diabetic mice. Type 1 diabetes was induced in both FGF...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Yan, Xiaoqing, Chen, Jun, Zhang, Chi, Zhou, Shanshan, Zhang, Zhiguo, Chen, Jing, Feng, Wenke, Li, Xiaokun, Tan, Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511354/
https://ncbi.nlm.nih.gov/pubmed/25823710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12530
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